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pentobarbital will lower the level or result of efavirenz by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Unfamiliar.pentobarbital will decrease the extent or outcome of celecoxib by affecting hepatic enzyme CYP2C9/10 metabolism. Insignificant/Importance Mysterious.pentobarbital decreases levels of vandetanib by aff